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It is a carbamate derivative that is used to treat alcohol addiction. Disulfiram inhibits an enzyme responsible for the oxidation of an alcohol metabolite, which accumulates and causes very unpleasant effects even with small amounts of alcohol, such as that found in some medications. Oral administration once a day.
At the date of the last update we did not find any published data on its excretion in breast milk.
Its high binding to plasma proteins makes it difficult to pass into breast milk.
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.
TOPICAL USE:
Topically it has been used to treat exoparasites such as lice or scabies. (Lajarin2022)
The poor plasma absorption of most topical dermatological preparations makes it unlikely that a significant amount will pass into breast milk. Do not apply on the breasts to prevent the infant from ingesting it.