Last update Jan. 15, 2023
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Disulfiram is also known as
Disulfiram in other languages or writings:
Disulfiram belongs to these groups or families:
|Tmax||1.8 - 3.3||hours|
|T½||6 - 11||hours|
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e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a carbamate derivative that is used to treat alcohol addiction. Disulfiram inhibits an enzyme responsible for the oxidation of an alcohol metabolite, which accumulates and causes very unpleasant effects even with small amounts of alcohol, such as that found in some medications. Oral administration once a day.
At the date of the last update we did not find any published data on its excretion in breast milk.
Its high binding to plasma proteins makes it difficult to pass into breast milk.
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.
Topically it has been used to treat exoparasites such as lice or scabies. (Lajarin2022)
The poor plasma absorption of most topical dermatological preparations makes it unlikely that a significant amount will pass into breast milk. Do not apply on the breasts to prevent the infant from ingesting it.