Last update July 16, 2017

ロルノキシカム

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Non-steroidal anti-inflammatory drug with analgesic properties related to oxycodone group. It is the only one with short half-life span.

At latest update relevant published data on its excretion into breast milk were not found.

Its high binding capacity to plasma proteins makes its excretion into breastmilk very unlikely. Another drug from the same group and same degree of protein binding capacity, Piroxicam (see specific info), has a negligible excretion into milk.

Until more data on this drug is available, a safer and known alternative may be preferable, especially in case of nursing infants who are less than one month old or a premature babies.


See below the information of this related product:

  • Piroxicam (Safe substance and/or breastfeeding is the best option.)

Alternatives

  • Flurbiprofen (Safe substance and/or breastfeeding is the best option.)
  • Ibuprofen (Safe substance and/or breastfeeding is the best option.)
  • Indomethacin; Indometacin (Safe substance and/or breastfeeding is the best option.)
  • Paracetamol (Safe substance and/or breastfeeding is the best option.)
  • Piroxicam (Safe substance and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

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Other names

ロルノキシカム is Lornoxicam in Japanese.

Is written in other languages:

ロルノキシカム is also known as

Group

ロルノキシカム belongs to this group or family:

Tradenames

Main tradenames from several countries containing ロルノキシカム in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 90 %
Molecular weight 372 daltons
Protein Binding 99 %
Tmax 0.5 hours
T½ 3 - 4 hours

References

  1. EMA. Lornoxicam. Ficha técnica. 2015 Full text (in our servers)
  2. EMA. Lornoxicam. Drug Summary. 2015 Full text (in our servers)
  3. Skjodt NM, Davies NM. Clinical pharmacokinetics of lornoxicam. A short half-life oxicam. Clin Pharmacokinet. 1998 Abstract
  4. Balfour JA, Fitton A, Barradell LB. Lornoxicam. A review of its pharmacology and therapeutic potential in the management of painful and inflammatory conditions. Drugs. 1996 Abstract
  5. Olkkola KT, Brunetto AV, Mattila MJ. Pharmacokinetics of oxicam nonsteroidal anti-inflammatory agents. Clin Pharmacokinet. 1994 Abstract

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