Last update July 16, 2017

Lornoxicam

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Non-steroidal anti-inflammatory drug with analgesic properties related to oxycodone group. It is the only one with short half-life span.

At latest update relevant published data on its excretion into breast milk were not found.

Its high binding capacity to plasma proteins makes its excretion into breastmilk very unlikely. Another drug from the same group and same degree of protein binding capacity, Piroxicam (see specific info), has a negligible excretion into milk.

Until more data on this drug is available, a safer and known alternative may be preferable, especially in case of nursing infants who are less than one month old or a premature babies.


See below the information of this related product:

  • Piroxicam (Safe product and/or breastfeeding is the best option.)

Alternatives

  • Flurbiprofen (Safe product and/or breastfeeding is the best option.)
  • Ibuprofen (Safe product and/or breastfeeding is the best option.)
  • Indomethacin; Indometacin (Safe product and/or breastfeeding is the best option.)
  • Paracetamol (Safe product and/or breastfeeding is the best option.)
  • Piroxicam (Safe product and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Lornoxicam is also known as


Lornoxicam in other languages or writings:

Tradenames

Main tradenames from several countries containing Lornoxicam in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 90 %
Molecular weight 372 daltons
Protein Binding 99 %
Tmax 0.5 hours
3 - 4 hours

References

  1. EMA. Lornoxicam. Ficha técnica. 2015 Full text (in our servers)
  2. EMA. Lornoxicam. Drug Summary. 2015 Full text (in our servers)
  3. Skjodt NM, Davies NM. Clinical pharmacokinetics of lornoxicam. A short half-life oxicam. Clin Pharmacokinet. 1998 Abstract
  4. Balfour JA, Fitton A, Barradell LB. Lornoxicam. A review of its pharmacology and therapeutic potential in the management of painful and inflammatory conditions. Drugs. 1996 Abstract
  5. Olkkola KT, Brunetto AV, Mattila MJ. Pharmacokinetics of oxicam nonsteroidal anti-inflammatory agents. Clin Pharmacokinet. 1994 Abstract

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