Last update July 3, 2022
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Esketamine Hydrochloride is also known as
Esketamine Hydrochloride in other languages or writings:
Esketamine Hydrochloride belongs to these groups or families:
Main tradenames from several countries containing Esketamine Hydrochloride in its composition:
|Oral Bioavail.||Intranasal: 48||%|
|Protein Binding||43 - 45||%|
|Tmax||0.3 - 0.7||hours|
|T½||7 - 12||hours|
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e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Esketamine is the S isomer of the anesthetic ketamine. It is administered intravenously or intramuscularly for the induction and maintenance of general anesthesia and as a supplement to regional and local anesthesia, and to provide analgesia in the emergency care. Intranasal esketamine is being investigated for treatment-resistant depression. The pharmacokinetics of esketamine is very similar to that of ketamine. (Martindale)
At latest update no published data on excretion into breast milk were found.
No problems have been observed in infants of mothers treated with ketamine. (Gilder 2021, Ortega 1999)
List of WHO essential medicines: ketamine is compatible with breastfeeding. (WHO-UNICEF 2002)
Until more published data regarding breastfeeding is available, the use of a known and safer alternative drug should be preferred, especially during the neonatal period and/or in case of premature infant.
See below the information of these related products: