Last update Nov. 3, 2023
Limited compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Chloramphenicol (systemic use) is also known as
Chloramphenicol (systemic use) in other languages or writings:
Chloramphenicol (systemic use) belongs to this group or family:
Main tradenames from several countries containing Chloramphenicol (systemic use) in its composition:
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Chloramphenicol is a broad-spectrum antibiotic whose use is limited due to its high risk of bone marrow toxicity. Oral or intravenous administration in 3 to 4 daily doses.
It is excreted in breast milk in very small amounts (Matsuda 1984, Plomp 1983, Havelka 1968), much lower than those used in pediatrics and neonatology.
Feeding refusal, drowsiness, vomiting and abdominal distension due to gas have been reported in infants under 15 days of age whose mothers took oral chloramphenicol. (Havelka 1972)
Although a case of aplastic anemia induced by chloramphenicol taken through breast milk has never been reported (WHO 2002), this serious complication of chloramphenicol is independent of the dose administered.
To be used during lactation only in absolutely necessary cases, avoiding it during the neonatal period and in case of prematurity. (Nahum 2006, WHO 2002)