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It is a carboxypenicillin used in the treatment of serious gram-negative infections, especially those due to Pseudomonas aeruginosa. Intravenous administration.
It is excreted into breastmilk in a clinically insignificant amount. (Matsuda 1984, von Kobyletzki 1983)
Its null oral bioavailability minimizes the passage into plasma of the infant from ingested breast milk, except in the premature and in the immediate neonatal period in which there may be greater intestinal permeability.
Although rare, the possibility of transient gastroenteritis due to alteration of the intestinal flora in infants whose mothers take antibiotics should be taken into account. (Ito 1993).
Expert authors consider the use of this medication to be safe during breastfeeding. (LacMed, Briggs 2015)