Last update June 23, 2022

C24H33N3O3S2

Limited compatibility

Unsafe. Moderate/severe adverse effects. Compatible under certain circumstances. Follow-up recommended. Use safer alternative or discontinue breastfeeding from 5 to 7 T ½ . Read Commentary.

Typical, first generation antipsychotic. Prochlorperazine is a phenothiazine derivative with general properties similar to those of chlorpromazine. It has been used in the treatment of schizophrenia and other psychoses. Oral or intramuscular administration (depot).

Since the last update we have not found published data on its excretion in breastmilk.

Product with very few bibliographic references, without known pharmacokinetic data and marketed in few countries.

Known safer alternatives are preferable (Parikh 2014), especially during the neonatal period and in the event of prematurity.

It has been withdrawn from the market in many countries. (Mustafa 2017)


See below the information of this related product:

Alternatives

  • Chlorpromazine (Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.)
  • Olanzapine (Safe product and/or breastfeeding is the best option.)
  • Perphenazine (Safe product and/or breastfeeding is the best option.)
  • Trifluoperazine Hydrochloride (Safe product and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

C24H33N3O3S2 is Pipotiazine in Molecular formula.

Is written in other languages:

C24H33N3O3S2 is also known as

Groups

C24H33N3O3S2 belongs to these groups or families:

Tradenames

Main tradenames from several countries containing C24H33N3O3S2 in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 458 daltons

References

  1. Mustafa FA. Switching away from pipotiazine palmitate: a naturalistic study. Ther Adv Psychopharmacol. 2017 Jan;7(1):25-28. Abstract
  2. Parikh T, Goyal D, Scarff JR, Lippmann S. Antipsychotic drugs and safety concerns for breast-feeding infants. South Med J. 2014 Abstract

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