Last update Jan. 2, 2023

塩酸トリペレナミン

Low Risk

Possibly safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

It is a first generation antihistamine, derived from ethylenediamine, with moderate antimuscarinic and sedative properties. It is used orally to treat hypersensitivity reactions, coughs, and the common cold, and topically to relieve skin itching from insect bites, contact with jellyfish or nettles, or minor skin irritations.

At the date of the last update we did not find any published data on its excretion in breast milk.

The paucity of known pharmacokinetic data does not allow prediction of the amount of its possible excretion in breast milk.

Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.

The small dose and poor plasma absorption of most topical dermatological preparations make it unlikely that a significant amount will pass into breast milk. Topical use would be compatible with breastfeeding (AEMPS 2017) as long as it is not applied to the chest or cleaned well before breastfeeding.

Alternatives

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

塩酸トリペレナミン is Tripelennamine Hydrochloride in Japanese.

Is written in other languages:

塩酸トリペレナミン is also known as

Groups

塩酸トリペレナミン belongs to these groups or families:

Tradenames

Main tradenames from several countries containing 塩酸トリペレナミン in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 292 daltons
Tmax 2 - 3 hours
2.9 - 4.4 hours

References

  1. AEMPS. Tripelenamina. Ficha técnica. 2017 Full text (in our servers)
  2. Yeh SY, Todd GD, Johnson RE, Gorodetzky CW, Lange WR. The pharmacokinetics of pentazocine and tripelennamine. Clin Pharmacol Ther. 1986 Jun;39(6):669-76. Abstract

Total visits

278

Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write us at elactancia.org@gmail.com

e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM