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It is a first generation antihistamine, derived from ethylenediamine, with moderate antimuscarinic and sedative properties. It is used orally to treat hypersensitivity reactions, coughs, and the common cold, and topically to relieve skin itching from insect bites, contact with jellyfish or nettles, or minor skin irritations.
At the date of the last update we did not find any published data on its excretion in breast milk.
The paucity of known pharmacokinetic data does not allow prediction of the amount of its possible excretion in breast milk.
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.
The small dose and poor plasma absorption of most topical dermatological preparations make it unlikely that a significant amount will pass into breast milk. Topical use would be compatible with breastfeeding (AEMPS 2017) as long as it is not applied to the chest or cleaned well before breastfeeding.