Last update June 17, 2017
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Penicillamine is also known as
Penicillamine in other languages or writings:
Penicillamine belongs to this group or family:
Main tradenames from several countries containing Penicillamine in its composition:
|Oral Bioavail.||40 - 70||%|
|Protein Binding||> 80||%|
|Tmax||1 - 3||hours|
|T½||1 - 3||hours|
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e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
A chelating agent that helps remove heavy metals such as copper, lead and mercury from the body.
Used to treat Wilson's disease, cystinuria, severe rheumatoid arthritis and chronic active hepatitis.
It is excreted in breast milk in clinically insignificant amounts (undetectable levels: Izumi 2012) and no problems have been observed in infants whose mothers have taken it (Sternlieb 2000, Messner 1998, Gregory 1983).
Oral bioavailability decreases by half in the presence of food, so its passing to the infant’s plasma via ingested breast milk would be very difficult
Copper and zinc levels in breast milk of mothers treated with penicillamine, trientine or zinc are normal according to more recent studies (Izumi 2012) and lower than normal according to older ones (Bunke 1989).
Cases of breast hyperplasia and hyperprolactinemia have been reported in patients treated with penicillamine (Craig 1988, Kahl 1985, Thew 1980).