Last update Aug. 11, 2022
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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N02AX06 is Tapentadol in ATC Code/s.Is written in other languages:
|VD||7.7 ± 1.4||l/Kg|
|Tmax||1.25 (Retard: 3 - 6)||hours|
|T½||4 (Retard: 6)||hours|
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e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain
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Opioid analgesic which is used for treatment of moderate to severe pain and of neuropathic pain associated with diabetic peripheral neuropathy. Oral administration.
At latest update, relevant data on its excretion into breast milk were not found.
Despite of a low molecular weight and a low serum-protein binding capacity that would favor excretion into the milk, its high value of volume distribution would permit a shorter permanence in the blood that would hamper its excretion.
A low oral bioavailability would hamper absorption from ingested mother's milk, except among newborn infants o prematures, who may attain an increased absorption capacity.
No problems have been observed in infants whose mothers have taken it. (Stollenwerk 2018)
Until more information on this drug is available, other options that are known to be safer are recommended, especially when the baby is a newborn or a premature. Follow-up of symptoms as sedation or gastrointestinal disorders is recommended.