Last update Aug. 16, 2022
Very Low Risk
It is a potent opioid agonist-antagonist analgesic used for the relief of moderate to severe pain, including labor pain, and as an adjunct to anesthesia. Administration by intravenous, intramuscular, or intranasal routes.
It is excreted in breast milk in negligible amount. (Pittman 1980)
The time of onset of breastfeeding was delayed in newborns whose mothers received analgesia at delivery with butorphanol or nalbuphine compared to those who did not receive analgesia, although in both groups it occurred on average within the first hour after birth. (Crowell 1994)
Expert authors consider the use of this medication during lactation to be probably compatible. (Hale, Reece 2017, Briggs 2015, Sachs 2013). American Academy of Pediatrics: medication usually compatible with breastfeeding.(AAP 2001)
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM