Last update Aug. 16, 2022
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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N02AD01 is Pentazocine in ATC Code/s.Is written in other languages:
N02AD01 is also known as
N02AD01 belongs to this group or family:
Main tradenames from several countries containing N02AD01 in its composition:
|VD||4.4 - 7.8||l/Kg|
|Tmax||1 - 3||hours|
|T½||2 - 3||hours|
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e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Pentazocine is an opioid analgesic derived from benzomorphan. It is used for the relief of moderate to severe pain, including labor pain. Oral, intramuscular, intravenous and subcutaneous administration.
A fecha de última actualización no encontramos datos publicados sobre su excreción en leche materna.
Its pharmacokinetic data (low molecular weight and moderate protein binding) makes transfer to breast milk possible, but its very high volume of distribution makes it difficult.
Its very low oral bioavailability (Sanofi 2018) minimizes the passage into plasma of the infant from ingested breast milk, except in the premature and in the immediate neonatal period in which there may be greater intestinal permeability.
It may increase prolactin levels. (Manner 1987)
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable (Sachs 2013), especially during the neonatal period and in the event of prematurity.