Last update July 22, 2022
Very Low Risk
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Fluticasone Furoate; Fluticasone Propionate is also known as Fluticasone.
Fluticasone Furoate; Fluticasone Propionate in other languages or writings:
Fluticasone Furoate; Fluticasone Propionate belongs to these groups or families:
Main tradenames from several countries containing Fluticasone Furoate; Fluticasone Propionate in its composition:
|Oral Bioavail.||oral: 1; inhal: 6 -18||%|
|Protein Binding||> 99||%|
|VD||4.2 - 8.6||l/Kg|
|Tmax||0.25 - 1||hours|
|T½||7.8 - 15.1||hours|
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e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a potent glucocorticoid used inhaled for asthma, nasally for rhinitis and polyps and applied topically on various skin disorders.
At latest update no relevant data on this subject were found in connection with breastfeeding.
Its pharmacokinetic characteristics (low systemic absorption, moderately elevated molecular weight, high plasma protein binding and large volume of distribution), make it highly unlikely that significant quantities will pass into breast milk. (Chambers 2021)
Its low oral bioavailability protects the infant from intestinal absorption.
Directly administered in childhood, only prolonged treatment with high doses of fluticasone can affect pituitary-adrenal function and growth. (Allen 2020, Todd 2002 & 1996)
Another similar inhaled corticosteroid (Budesonide) is excreted in breast milk in negligible amounts.
Several medical societies and expert authors consider topical, systemic or inhaled steroid medication to be safe or probably compatible with breastfeeding. (Hale, LactMed, Middleton 2020, Briggs 2015, Schaefer 2015, Amir 2011, National Asthma 2004, Ellsworth 1994)
Whenever a treatment for nipple eczema or dermatitis is required, the lowest potency steroid compound should be used. It should be applied right after the feed to make sure it has disappeared before the next nursing. Otherwise, wipe cream out with a clean gauze. Do not continuously use for longer than a week. Reportedly, a case of mineral-steroid toxicity has occurred due to continuous use of cream on the nipple. (De Stefano 1983)
Creams, gels or similar products that contain paraffin or mineral oil should not be used on the nipple to avoid absorption by the infant.(Concin 2008, Noti 2003)