Last update Oct. 9, 2016

C26H29FN2O2

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Antihistamine for topical use both on nose and eye.

Plasma concentrations reached are very low and, according to the manufacturer, it is excreted into breastmilk in clinically non-significant amount at 0.3 to 0.6% of maternal dose: 1.5 to 3 micrograms.

As in most ophthalmic and nasal topically used preparations, the tiny dose and poor levels in the blood, render it compatible with breastfeeding.

Alternatives

We do not have alternatives for C26H29FN2O2 since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

C26H29FN2O2 is Levocabastine Hydrochloride in Molecular formula.

Is written in other languages:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. Oft 30-60. Nas 60-80 %
Molecular weight 457 daltons
Protein Binding 55 %
VD 1.2 l/Kg
Tmax 2 hours
35 - 40 hours

References

  1. AEMPS. Levocabastina Nasal. Ficha técnica. 2016 Full text (in our servers)
  2. AEMPS. Levocabastina oftálmica. Ficha técnica. 2016 Full text (in our servers)
  3. J & J. Levocabastine. Drug Summary. 2010 Full text (in our servers)

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