Last update June 30, 2025

Levocabastine Hydrochloride

Compatible

Safe product and/or breastfeeding is the best option.

Topical, nasal and ophthalmic antihistamine.

According to the manufacturer, plasma concentrations achieved after nasal or ophthalmic administration are very low and are eliminated in breast milk in clinically insignificant amounts, 0.3-0.6% of the maternal dose: 1.5 to 3 micrograms. (AEMPS 2021 and 2020, J&J 2010)

As with most topical ophthalmic and nasal preparations, the tiny dose and its low passage into the bloodstream make it compatible with breastfeeding.

Alternatives

We do not have alternatives for Levocabastine Hydrochloride since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Levocabastine Hydrochloride in other languages or writings:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. Oft: 30-60. Nas: 60-80 %
Molecular weight 457 daltons
Protein Binding 55 %
VD 1.2 l/Kg
Tmax 1 - 2 hours
35 - 40 hours

References

  1. AEMPS. Levocabastina Nasal. Ficha técnica. 2021 Full text (in our servers)
  2. AEMPS. Levocabastina oftálmica. Ficha técnica. 2020 Full text (in our servers)
  3. J & J. Levocabastine. Drug Summary. 2010 Full text (in our servers)

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