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Acemetacin, a compound of indomethacin, is a nonsteroidal anti-inflammatory drug (NSAID). Its pharmacological activity is due to acemetacin and its main metabolite, indomethacin. It is used in rheumatoid arthritis, osteoarthritis, and low back pain, and for postoperative pain and inflammation. Oral administration in several doses per day.
Since the last update we have not found published data on its excretion in breastmilk.
Its pharmacokinetic data (very high percentage of protein binding, moderately high molecular weight and very wide volume of distribution) make it highly unlikely that significant quantities will pass into breast milk.
The literature on this drug is very scarce.
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives may be preferable, especially during the neonatal period and in the event of prematurity.