Last update Oct. 30, 2023


Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Alvimopan is an opioid antagonist used to reduce the healing time of postoperative ileus of the upper or lower gastrointestinal tract following surgical procedures involving bowel resection with primary anastomosis. Oral administration twice daily for 7 days after surgery.

At the time of the last update, we found no published data on its excretion in breast milk.

Its large volume of distribution, high percentage of binding to plasma proteins and moderately high molecular weight make it unlikely to pass into breast milk in clinically significant quantities.

Its very low oral bioavailability makes it difficult to pass into infant plasma from ingested breast milk.


We do not have alternatives for A06AH02.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

A06AH02 is Alvimopan in ATC Code/s.

Is written in other languages:


A06AH02 belongs to this group or family:


Main tradenames from several countries containing A06AH02 in its composition:


Variable Value Unit
Oral Bioavail. 6 %
Molecular weight 425 daltons
Protein Binding 80 - 94 %
VD 0.42 (0.3 - 0.6) l/Kg
pKa 3.71 -
Tmax 2 hours
10 - 18 hours


  1. FDA. Alvimopan (Entereg). Drug Summary. 2008 Full text (link to original source) Full text (in our servers)

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