Last update: Nov. 26, 2014
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
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Opioid analgesic which is used for treatment of chronic pain.
At latest update, relevant data on its excretion into breast milk were not found.
Despite of a low molecular weight and a low serum-protein binding capacity that would favor excretion into the milk, its high value of volume distribution would permit a shorter permanence in the blood that would hamper its excretion.
A low oral bioavailability would hamper absorption from ingested mother's milk, except among newborn infants o prematures, who may attain an increased absorption capacity.
The risk for the infants would be minimized if the breast feed is avoided within 1 to 4 hours (non-depot formulation), or, within 3 to 6 hours (depot formulation) after taking medication.
Until more information on this drug is available, other options that are known to be safer are recommended, especially when the baby is a newborn or a premature.
Follow-up of symptoms as sedation or gastrointestinal disorders is recommended.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
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