Last update: Oct. 31, 2018

S01EB09

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Acetylcholine is found naturally in the body; it is a hormonal neurotransmitter which intervenes in the transmission of nerve impulses.
It is used as an ophthalmic topical preparation to induce miosis during surgery on the anterior segment of the eye.

Since the last update we have not found published data on its excretion in breastmilk.

Given that the dose and absorption to the systemic circulation are minimal and that it is rapidly metabolized by the acetylcholinesterase enzyme in harmless products (choline and acetic acid), it is very unlikely to be excreted in milk in significant amounts (PDR 2018, Briggs 2017, LactMed2015 ).

No problems are anticipated for breastfeeding after the operation unless the mother shows signs of systemic absorption: bradycardia, hypotension, suffocation, respiratory distress, sweating, etc.

Alternatives

We do not have alternatives for S01EB09.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

S01EB09 is Acetylcholine Chloride in ATC Code/s.

Is written in other languages:

Group

S01EB09 belongs to this group or family:

Tradenames

Main tradenames from several countries containing S01EB09 in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 182 daltons

References

  1. PDR. Acetylcholine (Miochol). PDR online. 2018 Full text (link to original source) Full text (in our servers)
  2. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. 11th edition (acces on line) 2017
  3. AEMPS-Novartis. Acetilcolina. Ficha técnica. 2016 Full text (in our servers)
  4. LactMed Acetylcholine. Drugs and Lactation Database (LactMed). 2015 Abstract Full text (link to original source)

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