Last update: Oct. 31, 2018
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.
Acetylcholine is found naturally in the body; it is a hormonal neurotransmitter which intervenes in the transmission of nerve impulses.
It is used as an ophthalmic topical preparation to induce miosis during surgery on the anterior segment of the eye.
Since the last update we have not found published data on its excretion in breastmilk.
Given that the dose and absorption to the systemic circulation are minimal and that it is rapidly metabolized by the acetylcholinesterase enzyme in harmless products (choline and acetic acid), it is very unlikely to be excreted in milk in significant amounts (PDR 2018, Briggs 2017, LactMed2015 ).
No problems are anticipated for breastfeeding after the operation unless the mother shows signs of systemic absorption: bradycardia, hypotension, suffocation, respiratory distress, sweating, etc.
We do not have alternatives for 氯乙酰胆碱.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.