Last update: Oct. 31, 2018

Acetylcholine Chloride

Low Risk for breastfeeding

Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Acetylcholine is found naturally in the body; it is a hormonal neurotransmitter which intervenes in the transmission of nerve impulses.
It is used as an ophthalmic topical preparation to induce miosis during surgery on the anterior segment of the eye.

Since the last update we have not found published data on its excretion in breastmilk.

Given that the dose and absorption to the systemic circulation are minimal and that it is rapidly metabolized by the acetylcholinesterase enzyme in harmless products (choline and acetic acid), it is very unlikely to be excreted in milk in significant amounts (PDR 2018, Briggs 2017, LactMed2015 ).

No problems are anticipated for breastfeeding after the operation unless the mother shows signs of systemic absorption: bradycardia, hypotension, suffocation, respiratory distress, sweating, etc.


We do not have alternatives for Acetylcholine Chloride.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Acetylcholine Chloride in other languages or writings:


Acetylcholine Chloride belongs to this group or family:


Main tradenames from several countries containing Acetylcholine Chloride in its composition:


Variable Value Unit
Molecular weight 182 daltons


  1. PDR. Acetylcholine (Miochol). PDR online. 2018 Full text (link to original source) Full text (in our servers)
  2. AEMPS-Novartis. Acetilcolina. Ficha técnica. 2016 Full text (in our servers)
  3. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. Tenth edition (acces on line) 2015
  4. LactMed Acetylcholine. Drugs and Lactation Database (LactMed). 2015 Abstract Full text (link to original source)

Total visits


Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write to us at

e-lactancia is a resource recommended by La Liga de la Leche, España from Spain

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM