Last update June 26, 2022
Monoamine oxidase inhibitor antidepressant (MAOI) with action and uses similar to phenelzine. Oral administration once or twice daily.
At the date of the last update we did not find any published data on its excretion in breast milk.
Its wide volume of distribution (DrugBank acc.2022, Mallinger 1986) make it highly unlikely that significant quantities will pass into breast milk.
Monitor sedation and/or irritability in the infant.
A 15-day-old infant with serious malformations and whose mother was taking tranylcypromine, pimozide, diazepam, and alprazolam since pregnancy had problems with abdominal distention and food intolerance. (Kennedy 2017)
May cause increased prolactin. (Price 1985)
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM