头孢氨苄

First generation cephalosporin. Oral administration.

Like most cephalosporins for which data are available, it is excreted in human milk in a clinically non-significant amount ^{(Ilett 2006, Matsuda 1984, Kafetzis 1981)}. The pediatric relative dose is well below 1%. ^{(van Wattum 2021)}

Few problems have been reported in infants whose mothers took it.

It can cause gastroenteritis by altering the intestinal flora of the infant. ^{(Ilett 2006, Benyamini 2005, Ito 1993)}

A case of allergic reaction to cephalexin through its own mother’s milk has been published on a previously sensitized infant after administration of another cephalosporin intravenously. ^{(Chu 2019)}

Cephalosporins are widely used in Pediatrics with very good tolerance, even from the neonatal period, so it is very unlikely that, in small amounts through their own mothers’milk, they can cause problems for the infant.

Cephalexin is an antibiotic indicated for mastitis. ^{(Amir 2014, Jahanfar 2013, Spencer 2008)}

Various medical societies and expert consensus consider the use of this medication safe during breastfeeding. ^{(de Sá Del Fiol 2016, Butler 2014, Rowe 2013, Kong 2013, Amir 2011, Bar-Oz 2003, Fulton 1992)}