Last update Oct. 14, 2022
Very Low Risk
Ticarcillin is a carboxypenicillin used in the treatment of serious gram-negative infections, especially those due to Pseudomonas aeruginosa. Clavulanic acid is a beta-lactamase inhibitor produced by Staphylococcus aureus that is used to improve the efficacy of beta-lactam antibiotics. Intravenous administration.
Ticarcillin is excreted into breastmilk in a clinically insignificant amount (Matsuda 1984, von Kobyletzki 1983). Data on the excretion of clavulanic acid in breast milk are unknown.
The null oral bioavailability of Ticarcillin minimizes the passage into plasma of the infant from ingested breast milk, except in the premature and in the immediate neonatal period in which there may be greater intestinal permeability.
Although rare, the possibility of transient gastroenteritis due to alteration of the intestinal flora in infants whose mothers take antibiotics should be taken into account. (Ito 1993).
Expert authors consider the use of this medication to be safe during breastfeeding. (LacMed, Briggs 2015)
We do not have alternatives for Ticarcillin Sodium + Clavulanic Acid since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2006 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM