Last update Feb. 5, 2022
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Sufentanil Citrate in other languages or writings:
Sufentanil Citrate belongs to this group or family:
Main tradenames from several countries containing Sufentanil Citrate in its composition:
|Oral Bioavail.||baja - poor||%|
|VD||0.2 - 4.9||l/Kg|
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e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
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Opioid analgesic similar to fentanyl but with much more powerful action. Indicated for the control of labor and postoperative pain, in combination with general or epidural anesthesia. Intravenous or epidural administration.
It is excreted in colostrum and breast milk in small amounts (Cuypers 1995) or is not detectable (Madej 1987) and no problems have been observed in infants of mothers treated with epidural sufentanil. (Cuypers 1995)
Intravenous administration of sufentanil in planned caesarean sections may delay the onset of breastfeeding. (Chi 2017)
Epidural administration of sufentanil during labor does not cause a delay in the initiation of breastfeeding (Xu 2020, Mauri 2015), especially if there is no separation of mother and baby (joint accommodation 24 hours a day) during the hospital stay. (Zuppa 2014)
Epidural administration of sufentanil during labor may (Mauri 2015) or may not (Xu 2020) be associated with a shorter duration of exclusive breastfeeding.
The impact of epidural anesthesia on infancy is controversial. (Howie 2006)
Expert authors consider the epidural administration of sufentanil to be probably compatible (Reece 2017, Briggs 2015, Nice 2004, Spigset 1994, Lee 1993) and, even together with fentanyl, the opioid analgesic of choice during breastfeeding. (Schaefer 2015)
Until more published data are known about this drug in relation to breastfeeding, known safer alternatives may be preferable, especially during the neonatal period and in the event of prematurity.