Last update May 2, 2022

Sucrose hydrogen sulphate basic aluminium salt; Sucrose octakis(hydrogen sulphate) aluminium complex; β-d-Fructofuranosyl-α-d-glucopyranoside octakis (hydrogen sulphate) aluminium complex

Compatible

Safe product and/or breastfeeding is the best option.

It is a glycoside-sulphate derivative (sucrose) plus aluminum.

 It is indicated in peptic ulcer and chronic gastritis. Oral administration two to six times a day.

At latest update no published data on excretion into breastmilk were found.



Pharmacokinetic data (virtually non-absorbed with a high molecular weight) make it very unlikely the excretion into breastmilk in significant amounts, which in addition it would not be absorbed through the infant's intestine.



Medication with authorized use on infants.

Several medical societies and expert authors consider the use of this medication possible during breastfeeding. (Hale, LactMed, Thélin 2022, Briggs 2015, Schaefer 2015, Mahadevan 2006, Richter 2005, Hagemann 1998, Broussard 1998)

A cream with sucralfate, zinc, and copper has been used to treat nipple cracks. (Talaee 2021)

Alternatives

We do not have alternatives for Sucrose hydrogen sulphate basic aluminium salt; Sucrose octakis(hydrogen sulphate) aluminium complex; β-d-Fructofuranosyl-α-d-glucopyranoside octakis (hydrogen sulphate) aluminium complex since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Other names

Sucrose hydrogen sulphate basic aluminium salt; Sucrose octakis(hydrogen sulphate) aluminium complex; β-d-Fructofuranosyl-α-d-glucopyranoside octakis (hydrogen sulphate) aluminium complex is Sucralfate in Chemical name.

Is written in other languages:

Group

Sucrose hydrogen sulphate basic aluminium salt; Sucrose octakis(hydrogen sulphate) aluminium complex; β-d-Fructofuranosyl-α-d-glucopyranoside octakis (hydrogen sulphate) aluminium complex belongs to this group or family:

Tradenames

Main tradenames from several countries containing Sucrose hydrogen sulphate basic aluminium salt; Sucrose octakis(hydrogen sulphate) aluminium complex; β-d-Fructofuranosyl-α-d-glucopyranoside octakis (hydrogen sulphate) aluminium complex in its composition:

List of 37 tradenames

Pharmacokinetics

Variable Value Unit
Oral Bioavail. < 5 %
Molecular weight 1.559 daltons
VD - l/Kg
Tmax - hours
T½ - hours
M/P ratio ≈ 0 -
Theoretical Dose ≈ 0 mg/Kg/d
Relative Dose ≈ 0 %

References

  1. LactMed. Drugs and Lactation Database (LactMed). Internet. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/ 2006 - Consulted on April 16, 2024 Full text (link to original source)
  2. Hale TW. Medications & Mothers' Milk. 1991- . Springer Publishing Company. Available from https://www.halesmeds.com Consulted on April 10, 2024 Full text (link to original source)
  3. Talaee R, Mohammadzadeh M, Rahimi H. Comparing the combination of copper, zinc, and sucralfate (Cicalfate®) with white soft paraffin in the treatment of cracked nipples. Iran J Dermatol. 2021;24:18–23. Full text (link to original source) Full text (in our servers)
  4. Thélin CS, Richter JE. Review article: the management of heartburn during pregnancy and lactation. Aliment Pharmacol Ther. 2020 Feb;51(4):421-434. Abstract
  5. Schaefer C, Peters P, Miller RK. Drugs During Pregnancy and Lactation. Treatment options and risk assessment. Elsevier, Third Edition. 2015
  6. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. Tenth edition (acces on line) 2015
  7. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  8. Richter JE. Review article: the management of heartburn in pregnancy. Aliment Pharmacol Ther. 2005 Nov 1;22(9):749-57. Review. Abstract Full text (in our servers)
  9. Broussard CN, Richter JE. Treating gastro-oesophageal reflux disease during pregnancy and lactation: what are the safest therapy options? Drug Saf. 1998 Oct;19(4):325-37. Review. Abstract
  10. Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact. 1998 Sep;14(3):259-62. Review. Abstract

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