Last update June 11, 2018
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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R06AX29 is Bilastine in ATC Code/s.
Is written in other languages:Main tradenames from several countries containing R06AX29 in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 61 | % |
Molecular weight | 464 | daltons |
Protein Binding | 84 - 90 | % |
VD | 4.1 - 4.5 | l/Kg |
Tmax | 0.9 - 1.4 | hours |
T½ | 10.9 - 14.5 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a second-generation antihistamine drug without sedative or antimuscarinic effects (AEMPS 2016, Wolthers 2013, Scaglione 2012, Conen 2011, Church 2011).
At latest update, relevant data on its excretion into breast milk were not found.
Due to a lack of sedative effect since it does not break through the blood-brain barrier (Scaglione 2012, Church 2011), and, a favorable pharmacokinetic profile (Togawa 2016, AEMPS 2016, Sádaba 2013), -high protein-binding capacity, and a medium oral bioavailability-, the risk for problems in the nursing infant is very low. However, until more and reliable data on this drug concerning breastfeeding is available, known safer options should be preferred, especially for breastfeeding mothers in the first month after birth or in case of prematurity.