Last update Oct. 29, 2024
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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ビラスチン is Bilastine in Japanese.
Is written in other languages:Main tradenames from several countries containing ビラスチン in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 61 | % |
Molecular weight | 464 | daltons |
Protein Binding | 84 - 90 | % |
VD | 4.1 - 4.5 | l/Kg |
pKa | 4.06 | - |
Tmax | 0.9 - 1.4 | hours |
T½ | 10.9 - 14.5 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Second generation antihistamine without sedative or antimuscarinic effect. Use in allergic rhinitis and conjunctivitis and urticaria. Oral administration once daily. ( AEMPS 2016, Wolthers 2013, Scaglione 2012, Conen 2011, Church 2011)
At the date of last update we found no published data on its excretion in breast milk.
Its lack of sedative effect because it does not cross the blood-brain barrier (Scaglione 2012, Church 2011) and its pharmacokinetic profile (Togawa 2016, AEMPS 2016, Sádaba 2013), -high percentage of plasma protein binding and volume of distribution and medium oral bioavailability-, make it unlikely to cause problems for the infant.
Until more data on this drug in relation to breastfeeding are known, safer alternatives are preferable, especially during the first month and in the case of mothers of premature infants.