Last update Nov. 7, 2024

Pirbuterol

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Bronchodilator with similar characteristics to salbutamol and Terbutaline. Use in asthma. Inhaled administration.

At the date of last update we did not find published data on its excretion in breast milk.

Terbutaline, a molecule of the same family, is excreted in negligible quantities in breast milk.

Several medical societies and expert authors consider the use of inhaled bronchodilators safe during lactation due to low maternal serum levels achieved. (Lactmed, Bendien 2024, National Asthma 2004, Nelson 2001, Ellsworth 1994)

Alternatives

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Other names

Pirbuterol is also known as


Pirbuterol in other languages or writings:

Groups

Pirbuterol belongs to these groups or families:

Tradenames

Main tradenames from several countries containing Pirbuterol in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 300 daltons
Tmax 0.1 hours
T½ 3 hours

References

  1. Bendien SA, de Kruif MD, Feitsma H, van Hoolwerff-Blikkendaal C, Huurne KK, Kuiterman A, Baranova EV, Wittkamp A, Brons A, Poulissen M, van der Meer AN. Summary of the Dutch Multidisciplinary Practice Guideline on Asthma and Pregnancy. J Allergy Clin Immunol Pract. 2024 Jul;12(7):1751-1762. Consulted on Nov. 7, 2024 Abstract
  2. LactMed. Drugs and Lactation Database (LactMed). Internet. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/ 2006 - Consulted on April 16, 2024 Full text (link to original source)
  3. National Asthma Education and Prevention Program Asthma and Pregnancy Working Group. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. 2004;1-57. None 2004 Full text (link to original source) Full text (in our servers)
  4. Nelson-Piercy C. Asthma in pregnancy. Thorax. 2001 Abstract Full text (link to original source) Full text (in our servers)
  5. Ellsworth A. Pharmacotherapy of asthma while breastfeeding. J Hum Lact. 1994 Abstract

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