Last update May 16, 2023
Very Low Risk
It is an analog of vecuronium, non-depolarizing muscle relaxant drug with a peripheral action, that is used as premedication for endotracheal intubation, general anesthesia and mechanical ventilation. Intravenous administration.
Since the last update we have not found published data on its excretion in breastmilk.
Its moderately elevated molecular weight and rapid half-life elimination period (about 15 minutes) make it highly unlikely that significant quantities will pass into breast milk. (Dalal 2014)
Also, its low oral bioavailability renders the pass of this agent to the infant's plasma highly unlikely.
Breastfed infants have not shown any problem after 1.5 to 5 hours of anesthesia time period with Rocuronio (additional drugs like Propofol, Remifentanil and Xenon were used). (Stuttmann 2010)
Rocuronium does not prevent a mother from breast feeding her baby shortly after recovering from anesthesia if she is awake and in good condition.
Experts authors consider the use of this medication to be probably compatible during breastfeeding. (Briggs 2015, Howie 2006)
We do not have alternatives for Org-9426 since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2006 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM