Last update Sept. 1, 2022

Ольмезартан Медоксомил

Low Risk

Possibly safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

It is an angiotensin II receptor antagonist with actions similar to those of losartan. It is indicated in the treatment of hypertension. Oral administration once a day.

At latest update, relevant published data on excretion into breast milk were not found.

Its high protein-binding capacity makes excretion into breast milk unlikely. In addition, a low oral bioavailability makes difficult the absorption towards the infant's plasma from ingested milk, except in prematures or newborns who may show an increased absorption.

Until more data on this medication is available, safer alternative drugs are preferred (Malachias 2016, Rowe 2013), especially in premature babies or during the neonatal period.


Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Ольмезартан Медоксомил is Olmesartan Medoxomil in Cyrillic.

Is written in other languages:


Ольмезартан Медоксомил belongs to these groups or families:


Main tradenames from several countries containing Ольмезартан Медоксомил in its composition:


Variable Value Unit
Oral Bioavail. 4.5 - 28.6 %
Molecular weight 559 daltons
Protein Binding 99 %
VD 0.2 - 0.4 l/Kg
pKa 0.89 -
Tmax 1 - 3 hours
10 - 15 hours


  1. Malachias MV, Figueiredo CE, Sass N, Antonello IC, Torloni MR, Bortolotto MRF L. 7th Brazilian Guideline of Arterial Hypertension: Chapter 9 - Arterial Hypertension in pregnancy Arq Bras Cardiol. 2016 Abstract Full text (link to original source) Full text (in our servers)
  2. AEMPS. Olmesartán. Ficha técnica. 2014 Full text (in our servers)
  3. Rowe H, Baker T, Hale TW. Maternal medication, drug use, and breastfeeding. Pediatr Clin North Am. 2013 Feb;60(1):275-94. Abstract
  4. Merck. Olmesartan. Drug Summary. 2013 Full text (in our servers)
  5. Tamargo j, Caballero R, Gómez R, Núñez L, Vaquero M y Delpón E. Características farmacológicas de los ARA-II. ¿Son todos iguales?. Rev Esp Cardiol Supl. 2006;6:10C-24C. 2006 Full text (in our servers)

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America

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