Last update April 15, 2024
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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C09CA08 is Olmesartan Medoxomil in ATC Code/s.
Is written in other languages:C09CA08 belongs to these groups or families:
Main tradenames from several countries containing C09CA08 in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 4.5 - 28.6 | % |
Molecular weight | 559 | daltons |
Protein Binding | 99 | % |
VD | 0.2 - 0.4 | l/Kg |
pKa | 0.89 | - |
Tmax | 1 - 3 | hours |
T½ | 10 - 15 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
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It is an angiotensin II receptor antagonist with actions similar to those of losartan. It is indicated in the treatment of hypertension. Oral administration once a day.
At latest update, relevant published data on excretion into breast milk were not found.
Its high protein-binding capacity makes excretion into breast milk unlikely. In addition, a low oral bioavailability makes difficult the absorption towards the infant's plasma from ingested milk, except in prematures or newborns who may show an increased absorption.
An infant whose mother was taking olmesartan (dose not reported) presented with weight loss and increased liver transaminases in the third week of life that resolved after stopping the medication. Salimova 2023)
Safer alternative drugs are preferred (Malachias 2016, Rowe 2013), especially in premature babies or during the neonatal period.