Last update Oct. 9, 2016

Mebeverine Hydrochloride

Low Risk

Moderately safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

Antispasmodic drug with direct effect on intestinal smooth muscle and little anticholinergic effects. Used for treatment of Irritable Bowel Syndrome.

At latest update no published data on excretion into breast milk were found.

Anticholinergic drugs may reduce milk production: take a minimum necessary dose and avoid long-term treatment whenever breastmilk were decreased.

Alternatives

We do not have alternatives for Mebeverine Hydrochloride.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

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Other names

Mebeverine Hydrochloride in other languages or writings:

Group

Mebeverine Hydrochloride belongs to this group or family:

Tradenames

Main tradenames from several countries containing Mebeverine Hydrochloride in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 466 daltons
Protein Binding 75 %
Tmax 1 - 3 hours
T½ 1. 1 - 2.5 hours

References

  1. AEMPS. Mebeverina. Ficha técnica. 2008 Full text (in our servers)
  2. Stockis A, Guelen PJ, de Vos D. Identification of mebeverine acid as the main circulating metabolite of mebeverine in man. J Pharm Biomed Anal. 2002 Abstract

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