Last update Jan. 16, 2021

氯磺丙脲

Low Risk

Moderately safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

Sulfonylurea that stimulates endogenous insulin secretion. May cause hypoglycemia.
Indicated in the treatment of type 2 diabetes.
Oral administration in one dose daily.

It is excreted in human milk in small amounts (Pfizer 2008), but it could be clinically significant (RID = 9%).

Until there is further published data on this drug in relation to breastfeeding, known safer alternatives may be preferable, especially during the neonatal period and in cases of prematurity.

Diet, exercise, and breastfeeding improve blood sugar levels.


See below the information of this related product:

Alternatives

  • Acarbose ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Glibenclamide ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Hypocaloric Diet ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Insulin ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Maternal Sport ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Metformin Hydrochloride ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Miglitol ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Tolbutamide ( Safe. Compatible. Minimal risk for breastfeeding and infant.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

氯磺丙脲 is Chlorpropamide in Chinese.

Is written in other languages:

Tradenames

Main tradenames from several countries containing 氯磺丙脲 in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 277 daltons
Protein Binding 96 %
Tmax 6 hours
33 hours
Theoretical Dose 0.75 mg/Kg/d
Relative Dose 9 %

References

  1. Pfizer. Chlorpropamide. Drug Summary. 2008 Full text (in our servers)

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