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It is a carbacefem antibacterial. Carbacefems are closely related to cephalosporins. Loracarbef is structurally similar to cefaclor, a second generation cephalosporin. Oral administration.
At latest update no published data on excretion into breast milk were found.
Most cephalosporins are excreted into milk in insignificant amounts from a therapeutic point of view (Rowe 2013, Fulton 1992) without reported complications in infants.
Cephalosporins are widely used in the Pediatric practice with a good tolerance, even in the neonatal period, so it is very unlikely that in small amounts through milk would be a cause of problems in the infant.
Although rare, the possibility of transient gastroenteritis due to alteration of the intestinal microbiome in infants whose mothers take antibiotics should be taken into account. (Ito 1993)
Several medical societies and expert authors consider it safe to use this medication during breastfeeding. (LactMed, Bar 2003)
Product with few bibliographic references and marketed in few countries.
Pending further published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in case of prematurity.