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Lemborexant is a dual orexin receptor antagonist used to treat insomnia in adults. Oral administration in one dose at bedtime.
At the date of the last update we did not find any published data on its excretion in breast milk.
Its pharmacokinetic data (high percentage of binding to plasma proteins, very large volume of distribution and moderately high molecular weight) explain the minimal passage into breast milk observed. (Rawal 2023, Saito 2023)
Infants exposed to this drug through breast milk should be monitored for excessive sedation and/or poor feeding. (FDA 2019)
Due to its sedative effect, it is not recommended to share a bed with the baby if this drug is being taken. (UNICEF 2018, 2017, 2014 and 2013, Landa 2012, ABM 2008, UNICEF 2006)