Last update Nov. 2, 2022
Very Low Risk
Imidazopyridine with benzodiazepine-like hypnotic effect. Used for insomnia. Oral administration once a day, usually at night before bedtime.
It is excreted in breast milk in clinically insignificant amounts. (Saito 2022 & 2022, Pons 1994 &1989)
No problems have been observed in infants whose mothers were taking it. (Saito 2022 apr)
Plasma levels of Zolpidem were not detected in these infants. (Saito 2022 oct)
Five nursing mothers who took twice the usual dose, excreted it into breast milk in a clinically non-significant amount, maximum at 3 hours and undetectable from 4-5 hours post-dose. (Hale, Chen 2010, Pons 1989)
Several experts consider the use of this medication safe or probably safe during breastfeeding (Hale, Briggs 2017), although known data are limited. (Uguz 2021)
American Academy of Pediatrics: medication usually compatible with breastfeeding. (AAP 2001).
It is recommended to check for sedation and/or lack of appetite in infants. Bed-sharing (co-sleeping) with the baby is not recommended if this drug are used. (ABM 2020 y 2008, UNICEF 2018, 2017, 2014 y 2013, Landa 2012, UNICEF 2006)
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM