Last update Dec. 13, 2019

クエン酸カリウム

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

It is used orally and intravenously to alkalize urine in the treatment of renal lithiasis and tubular acidosis.
After absorption, it is metabolized to bicarbonate. It has very low toxicity at the usual therapeutic doses (AEMPS 2012).
It is also used as a food additive (E 332) to reduce acidity.

Since the last update we have not found published data on its excretion in breastmilk.

Potassium is an ion present in breastmilk (Allen 1991) at a concentration 6 to 7 times greater than that of plasma: 18.3 ± 5.7 mEq/L. Like other monovalent ions, it freely enters and exits milk, inversely to the concentration of lactose (Lawrence 2016 p119). In the body, it is found mostly within cells, with a plasma concentration within specific limits (3.5 to 5.5 mEq/L).

Experts consider it compatible with breastfeeding (Briggs 2018).

Only in rare cases of maternal disease with high concentration of potassium in maternal blood (hyperkalaemia), can it increase its concentration in breastmilk, in which case possible gastrointestinal disorders and elevated plasma levels should be monitored in the infant.


See below the information of this related product:

Alternatives

We do not have alternatives for クエン酸カリウム since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

クエン酸カリウム is Potassium Citrate in Japanese.

Is written in other languages:

クエン酸カリウム is also known as

Groups

クエン酸カリウム belongs to these groups or families:

Tradenames

Main tradenames from several countries containing クエン酸カリウム in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 306 daltons

References

  1. Hale TW. Medications & Mothers' Milk. 1991- . Springer Publishing Company. Available from https://www.halesmeds.com Consulted on March 17, 2022 Full text (link to original source)
  2. Lawrence RA, Lawrence RM. Breastfeeding. A guide for the medical profession. Eighth Edition. Philadelphia: Elsevier; 2016
  3. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. Tenth edition (acces on line) 2015
  4. OMS. Ingesta de potasio en adultos y niños. Resumen. Directrices 2013 Full text (in our servers)
  5. AEMPS. Citrato de potasio. Ficha técnica. 2012 Full text (in our servers)
  6. WHO. Potassium intake for adults and children. Guideline 2012 Full text (in our servers)
  7. Hall Moran V, Lowe N, Crossland N, Berti C, Cetin I, Hermoso M, Koletzko B, Dykes F. Nutritional requirements during lactation. Towards European alignment of reference values: the EURRECA network. Matern Child Nutr. 2010 Oct;6 Suppl 2:39-54. Abstract Full text (link to original source) Full text (in our servers)
  8. Mission Ph.C. Potassium Citrate. Drug Summary. 2010 Full text (in our servers)
  9. Allen JC, Keller RP, Archer P, Neville MC. Studies in human lactation: milk composition and daily secretion rates of macronutrients in the first year of lactation. Am J Clin Nutr. 1991 Abstract
  10. Ereman RR, Lönnerdal B, Dewey KG. Maternal sodium intake does not affect postprandial sodium concentrations in human milk. J Nutr. 1987 Abstract

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