Last update Dec. 13, 2019
Very Low Risk
It is used orally and intravenously to alkalize urine in the treatment of renal lithiasis and tubular acidosis.
After absorption, it is metabolized to bicarbonate. It has very low toxicity at the usual therapeutic doses (AEMPS 2012).
It is also used as a food additive (E 332) to reduce acidity.
Since the last update we have not found published data on its excretion in breastmilk.
Potassium is an ion present in breastmilk (Allen 1991) at a concentration 6 to 7 times greater than that of plasma: 18.3 ± 5.7 mEq/L. Like other monovalent ions, it freely enters and exits milk, inversely to the concentration of lactose (Lawrence 2016 p119). In the body, it is found mostly within cells, with a plasma concentration within specific limits (3.5 to 5.5 mEq/L).
Experts consider it compatible with breastfeeding (Briggs 2018).
Only in rare cases of maternal disease with high concentration of potassium in maternal blood (hyperkalaemia), can it increase its concentration in breastmilk, in which case possible gastrointestinal disorders and elevated plasma levels should be monitored in the infant.
We do not have alternatives for A12BA02 since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM