Last update March 29, 2023

Iopanoic Acid

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Radiological contrast medium with 67% iodine used in cholecystography and cholangiography. Oral administration.

Iopanoic acid is excreted in breast milk in a clinically insignificant amount: 7 to 30 mg in 24 hours, <0.1% of the maternal dose, and no problems have been observed in nursing infants whose mothers received it. (Holmdahl 1956)

American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001). Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs: compatible with Breastfeeding. (WHO 2002)

The various Iodinated contrast media for imaging examinations (X-rays, CT scans) are considered compatible with breastfeeding since they are rapidly eliminated with little or no release of iodine, not metabolized and virtually not absorbed when taken by mouth. They are structurally very similar to each other and one of them is their data no or minimal excretion in milk.

Given the low lipid solubility of the iodinated contrast, less than 1% of the dose administered to the mother just passing milk. Due to their low oral bioavailability, intestinal absorption is less than 1% of the dose that he may take the infant. The maximum dose just getting the baby is less than 0.01% of the maternal dose, which represents less than 1% of the dose administered to a nursing practice that is a radiological contrast examination.

Most experts and radiology scientific societies agree that after a radiological iodinated contrast examination is not necessary to wait no time to nurse.

American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.


See below the information of this related product:

Alternatives

We do not have alternatives for Iopanoic Acid since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Iopanoic Acid in other languages or writings:

Group

Iopanoic Acid belongs to this group or family:

Tradenames

Main tradenames from several countries containing Iopanoic Acid in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 571 daltons
Protein Binding 97 %
pKa 2.85 -
Tmax 17 hours
24 hours
Relative Dose 0.08 %

References

  1. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)
  2. AAP - American Academy of Pediatrics Committee on Drugs. Transfer of drugs and other chemicals into human milk. Pediatrics. 2001 Sep;108(3):776-89. Abstract Full text (link to original source) Full text (in our servers)

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