Last update Nov. 20, 2024

(Iodide Radiopaque Agent)

Compatible

Safe product and/or breastfeeding is the best option.

The various Iodinated contrast media for imaging examinations (X-rays, CT scans) are considered compatible with breastfeeding (Mattsson 2021, ACR 2018, CO723 2017, Cova 2014, Quintana 2014, Webb 2004, Chen 2008) since they are rapidly eliminated with little or no release of iodine, not metabolized (Rosati 1994) and virtually not absorbed when taken by mouth. They are structurally very similar to each other and one of them is their data no or minimal excretion in milk.

Given the low lipid solubility of the iodinated contrast, less than 1% of the dose administered to the mother just passing milk. Due to their low oral bioavailability, intestinal absorption is less than 1% of the dose that he may take the infant. The maximum dose just getting the baby is less than 0.01% of the maternal dose, which represents less than 1% of the dose administered to a nursing practice that is a radiological contrast examination. (Nielsen 1987)

Most experts and radiology scientific societies agree that after a radiological iodinated contrast examination is not necessary to wait no time to nurse. (Mattsson​​​​​​​ 2021, ACR, Mitchell 2019, ACOG  2017, Cova 2014, Quintana 2014, Sachs 2013, Tremblay 2012, Chen 2008, Newman 2007, Webb 2005, Nielsen 1987)


See below the information of this related group:

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Other names

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Group

(Iodide Radiopaque Agent) belongs to this group or family:

References

  1. Mattsson S, Leide-Svegborn S, Andersson M. X-RAY AND MOLECULAR IMAGING DURING PREGNANCY AND BREASTFEEDING-WHEN SHOULD WE BE WORRIED? Radiat Prot Dosimetry. 2021 Oct 12;195(3-4):339-348. Abstract Full text (link to original source)
  2. Mitchell KB, Fleming MM, Anderson PO, Giesbrandt JG; Academy of Breastfeeding Medicine.. ABM Clinical Protocol #30: Radiology and Nuclear Medicine Studies in Lactating Women. Breastfeed Med. 2019 Jun;14(5):290-294. Abstract
  3. ACOG - American College of Obstetricians and Gynecologists. Committee Opinion No. 723: Guidelines for Diagnostic Imaging During Pregnancy and Lactation. Obstet Gynecol. 2017 Oct;130(4):e210-e216. Abstract
  4. Quintana Rodríguez I. Uso de contrastes radiológicos en la mujer lactante y en niños.. CbSERAM nº 8/14 – Agosto 2014 Abstract Full text (link to original source) Full text (in our servers)
  5. Cova MA, Stacul F, Quaranta R, Guastalla P, Salvatori G, Banderali G, Fonda C, David V, Gregori M, Zuppa AA, Davanzo R. Radiological contrast media in the breastfeeding woman: a position paper of the Italian Society of Radiology (SIRM), the Italian Society of Paediatrics (SIP), the Italian Society of Neonatology (SIN) and the Task Force on Breastfeeding, Ministry of Health, Italy. Eur Radiol. 2014 Abstract
  6. Sachs HC; Committee On Drugs. The transfer of drugs and therapeutics into human breast milk: an update on selected topics. Pediatrics. 2013 Sep;132(3):e796-809. Abstract Full text (link to original source) Full text (in our servers)
  7. Tremblay E, Thérasse E, Thomassin-Naggara I, Trop I. Quality initiatives: guidelines for use of medical imaging during pregnancy and lactation. Radiographics. 2012 Abstract Full text (link to original source) Full text (in our servers)
  8. Wang PI, Chong ST, Kielar AZ, Kelly AM, Knoepp UD, Mazza MB, Goodsitt MM. Imaging of pregnant and lactating patients: part 1, evidence-based review and recommendations. AJR Am J Roentgenol. 2012 Abstract Full text (link to original source) Full text (in our servers)
  9. ACR - American College of Radiology Committee on Drugs and Contrast Media. ACR Manual on Contrast Media. 2010- American College of Radiology. Abstract Full text (link to original source)
  10. Chen MM, Coakley FV, Kaimal A, Laros RK Jr. Guidelines for computed tomography and magnetic resonance imaging use during pregnancy and lactation. Obstet Gynecol. 2008 Abstract
  11. Newman J. Breastfeeding and radiologic procedures. Can Fam Physician. 2007 Abstract Full text (link to original source) Full text (in our servers)
  12. Webb JA, Thomsen HS, Morcos SK; Members of Contrast Media Safety Committee of European Society of Urogenital Radiology (ESUR). The use of iodinated and gadolinium contrast media during pregnancy and lactation. Eur Radiol. 2005 Jun;15(6):1234-40. Epub 2004 Dec 18. Abstract
  13. Rosati G. Clinical pharmacology of iomeprol. Eur J Radiol. 1994 May;18 Suppl 1:S51-60. Review. Abstract
  14. Nielsen ST, Matheson I, Rasmussen JN, Skinnemoen K, Andrew E, Hafsahl G. Excretion of iohexol and metrizoate in human breast milk. Acta Radiol. 1987 Abstract

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