Last update Oct. 29, 2023
Limited compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Thank you for helping to protect and promote breastfeeding.
حمض أمينوكابروئيك is Aminocaproic Acid in Arabic.
Is written in other languages:حمض أمينوكابروئيك belongs to this group or family:
Main tradenames from several countries containing حمض أمينوكابروئيك in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 100 | % |
Molecular weight | 131 | daltons |
Protein Binding | 10 | % |
VD | 0.3 - 0.4 | l/Kg |
pKa | 4.73 | - |
Tmax | 1.2 | hours |
T½ | 2 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Aminocaproic acid is an amino acid, similar to lysine and arginine, with antifibrinolytic properties used in the treatment and prophylaxis of bleeding associated with excessive fibrinolysis. It has been used in the prophylaxis of hereditary angioedema, to induce postoperative coagulation and, together with factor VIII or IX, in hemophilia. Oral or intravenous administration.
At the time of the last update, we found no published data on its excretion in breast milk.
Its high volume of distribution makes it difficult to pass into breast milk.
To minimize the possible exposure of the drug through breast milk, it is advisable to wait 3 to 5 T1/2 (6 to 10 hours) after the last dose before resuming breastfeeding. This is not necessary if the drug has been administered at delivery or in the immediate postpartum period, since the small amount of colostrum that the newborn takes in does not contain a significant amount of the drug.
Expert authors consider safer alternatives known to be preferable during lactation (Yeich 2023, Évora 2021, Hawke 2016), especially during the neonatal period and in case of prematurity.