Last update July 16, 2017

Hippocastani semen

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

The seeds, bark and leaves are used. It contains Aescin and esculin (see specific info), with a vasoprotector effect and devoid of toxicity at normal doses.

At latest update no published data on excretion into breast milk was found.

Side effects are rare and mild.
The Commission E of German Ministry of Health does not contraindicate the use of seed extract during infancy.

Given its lack of toxicity at normal doses, a moderate consumption during lactation would pose a very low risk.

For topical preparations, do not apply it on the chest or thoroughly clean it up before breastfeeding.

See below the information of these related products:

  • Aescin ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Aesculin ( Safe. Compatible. Minimal risk for breastfeeding and infant.)


We do not have alternatives for Hippocastani semen since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Hippocastani semen is Horse Chestnut in Latin, botanical name.

Is written in other languages:

Hippocastani semen is also known as


Main tradenames from several countries containing Hippocastani semen in its composition:

  • Muscoril Trauma™. Contains other elements than Hippocastani semen in its composition


Variable Value Unit
Oral Bioavail. Baja - Poor %


  1. Zając M, Wiśniewski M, Sein Anand J. [Intoxication by powdered seeds of horse chestnut (Aesculus hippocastanum) used nasally as snuff - a case report]. Przegl Lek. 2014 Abstract
  2. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane Database Syst Rev. 2012 Abstract
  3. Methlie CB, Schjøtt J. [Horse chestnut--remedy for chronic venous insufficiency]. Tidsskr Nor Laegeforen. 2009 Abstract
  4. EMA. Hippocastani semen. Community Herbal Monograph. 2009 Full text (in our servers)
  5. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane Database Syst Rev. 2004 Abstract
  6. WHO. World Health Organization. Geneva. WHO monographs on selected medicinal plants. Volume 2. WHO monographs. 2004 Full text (link to original source) Full text (in our servers)
  7. Siebert U, Brach M, Sroczynski G, Berla K. Efficacy, routine effectiveness, and safety of horsechestnut seed extract in the treatment of chronic venous insufficiency. A meta-analysis of randomized controlled trials and large observational studies. Int Angiol. 2002 Abstract

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2006 of United States of America

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