Last update Aug. 3, 2022
Very Low Risk
We do not have alternatives for Fosfomycin Trometamol, Fosfomycin Tromethamine since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
Fosfomycin Trometamol, Fosfomycin Tromethamine is also known as
Fosfomycin Trometamol, Fosfomycin Tromethamine in other languages or writings:
Fosfomycin Trometamol, Fosfomycin Tromethamine belongs to this group or family:
Main tradenames from several countries containing Fosfomycin Trometamol, Fosfomycin Tromethamine in its composition:
|Oral Bioavail.||Trom: 30 - 58; Calc: 12||%|
|VD||1.9 ± 0.6||l/Kg|
|Tmax||2 - 4||hours|
|T½||4 - 6||hours|
|Theoretical Dose||0.54 - 0.72||mg/Kg/d|
|Relative Dose||1.6 - 4.3||%|
|Ped.Relat.Dose||0.27 - 0.72||%|
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e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Fosfomycin is a bactericidal antibacterial indicated in the treatment of uncomplicated acute cystitis in adult women and adolescents. One to three time daily oral administration for one to three days. Possible intravenous administration.
It is excreted in human milk in insignificant amounts. (Kirby 1977)
Its use is approved in infants less than one year of age.
Its low oral bioavailability makes it difficult for the infant to pass into plasma from ingested mothers’ milk, except in premature infants and during the immediate neonatal period in which there may be greater intestinal permeability.
Food and calcium in the mothers’ milk make intestinal absorption even more difficult (Hale); calcium fosfomycin is very poorly absorbed. (Lebedevs 2020, Bergan 1990)
Although rare, the possibility of transient gastroenteritis due to altered intestinal flora should be considered in infants whose mothers take antibiotics. (Briggs 2015, Benyamini 2005)