Last update Sept. 19, 2016

Fesoterodine

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Antimuscarinic agent with atropine-like action. It is metabolized in Tolterodine

At latest update no published data on excretion into breast milk were found.

Until more published data on this drug in relation to breastfeeding is available, a known safer alternative as Tolterodine should be preferred with more favorable pharmacokinetics characteristics for lactation (e.g. high protein-binding capacity, faster elimination and lower oral bioavailability), particularly during the neonatal period and prematurity case.

Take as smallest dose as possible and avoid long-term use since anticholinergics can reduce milk production.

Monitoring anticholinergic symptoms in infants (dry mouth, constipation ..) is warranted.

Alternatives

  • Tolterodine Tartrate (Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Fesoterodine is also known as


Fesoterodine in other languages or writings:

Tradenames

Main tradenames from several countries containing Fesoterodine in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 52 %
Molecular weight 412 daltons
Protein Binding 50 %
VD 2.4 l/Kg
Tmax 5 hours
7 hours

References

  1. EMA. Fesoterodina. Ficha técnica. 2014 Full text (in our servers)
  2. EMA. Fesoterodine. Drug Summary. 2014 Full text (in our servers)

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