Last update June 18, 2022
Very Low Risk
It is excreted into breastmilk in a clinically non-significant amount. (Yoshida 1997, Ilett 1992, Rees 1976)
Plasma levels in the infant have been found very low. (Yoshida 1997, Ilett 1992)
No side effects have been observed in infants of mothers treated with dothiepin. (Yoshida 1997, Buist 1995, Ilett 1992)
Dothiepin can produce galactorrhea and hyperprolactinemia. (Gadd 1987)
Expert authors consider the use of this medication safe during lactation (LactMed, Hale, Wisner 1996). Some authors consider other alternatives to be safer during the neonatal period and in case of prematurity. (Weissman 2004)
Women suffering from depression during pregnancy need more breastfeeding support due to their increased risk of breastfeeding problems and early weaning. (Grzeskowiak 2018, Leggett 2017, Venkatesh 2017, Gorman 2012)
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM