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Exenatide is an incretin hormone analog used in the treatment of type 2 diabetes.
Subcutaneous administration every 24 hours.
Since the last update we have not found published data on its excretion in breast milk.
Its pharmacokinetic data (high molecular weight, large volume of distribution and and short half life) make it very unlikely that significant amounts will pass into breast milk. (Serrano 2014)
Due to its protein nature, it deteriorates in the gastrointestinal tract, not being absorbed (Serrano 2014). This low oral bioavailability would make it difficult for it to pass to the infant’s plasma ingesting breast milk, except in preterm infants and in the immediate neonatal period when there may be increased intestinal permeability.
Diet, exercise, and breastfeeding improve blood sugar levels.