Last update July 16, 2015

CGP-25827A

Compatible

Safe product and/or breastfeeding is the best option.

Bronchodilator of long-lasting action.

At latest update no published data on excretion into breast milk were found.

Terbutaline which is a compound closely related to Formoterol is excreted into breast milk in non-significant amount.
Salmeterol, another compound with similar characteristics, is also non-significantly excreted.
With a relatively high molecular weight, excretion into breast milk seems unlikely.

Expert consensus states that the use of inhaled bronchodilators is compatible with breastfeeding due to a minimal absorption and low levels achieved in the mother's plasma.

Inhaled therapy with bronchodilators is preferred since they use a lower dose (less likelihood of excretion into milk)

Alternatives

  • Salmeterol (Safe product and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

CGP-25827A is also known as Formoterol. Here it is a list of alternative known names::


CGP-25827A in other languages or writings:

Group

CGP-25827A belongs to this group or family:

Tradenames

Main tradenames from several countries containing CGP-25827A in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. > 90% %
Molecular weight 805 daltons
Protein Binding 64 %
Tmax 0.1 hours
10 hours

References

  1. Middleton PG, Gade EJ, Aguilera C, MacKillop L, Button BM, Coleman C, Johnson B, Albrechtsen C, Edenborough F, Rigau D, Gibson PG, Backer V. ERS/TSANZ Task Force Statement on the management of reproduction and pregnancy in women with airways diseases. Eur Respir J. 2020 Feb 6;55(2). pii: 1901208. Abstract Full text (link to original source) Full text (in our servers)
  2. National Asthma Education and Prevention Program Asthma and Pregnancy Working Group. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. 2004;1-57. None 2004 Full text (link to original source) Full text (in our servers)
  3. Nelson-Piercy C. Asthma in pregnancy. Thorax. 2001 Abstract Full text (link to original source) Full text (in our servers)
  4. Ellsworth A. Pharmacotherapy of asthma while breastfeeding. J Hum Lact. 1994 Abstract

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America

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